Microtome

Your Professional Microtome Supplier
 
 

We are your professional Microtome manufacturer, in 2015, Kuohai was recognized as a "national high-tech enterprise". "Kuohai Medical Technology" has five subsidiaries, including Hubei Xiaogan Kuohai Medical Technology Co., Ltd., Xiaogan Kuohai Medical Technology Co., Ltd., Hubei Haishi Industrial Co., Ltd., Xiaogan Ruifeng Electronic Technology Co., Ltd., Xiaogan Dinghang Decoration Engineering Co., Ltd., and its product range covers medical equipment, biotechnology, electronic technology, high-end building materials, decoration engineering and other industries.

 

Why Choose Us

 

 

Our company
Xiaogan Kuohai Medical Technology Co.,Ltd. is a rare domestic pathology instrument manufacturing company with a widespread user base throughout China. It is also one of the few companies in the domestic and international industry capable of researching, developing, and producing a complete set of pathology instruments and consumables. In 2014, the company established a modern production and processing base.

 

Our services
All our equipment will be equipped with very detailed instructions, so that your operation is simple and straightforward, and no questions arise. At kuohai medical technology, we guarantee the quality and durability of our products.

 

Our products
The product range involves medical equipment, biotechnology, electronic technology, high-end building materials, decoration engineering and other industries.

 

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Advantages of Microtome
 
 
 

Micrometer-driven specimen advance

 

Microtomes are equipped with a micrometer-driven specimen advance mechanism that allows precise control over section thickness. This feature enables researchers to obtain consistent and reproducible sections, crucial for accurate analysis.

 
 

Adjustable knife angle and speed

 

Microtomes provide the flexibility to adjust the knife angle and speed, allowing researchers to optimize sectioning parameters based on tissue type and characteristics. This adaptability ensures optimal cutting performance and minimizes tissue damage.

 
 

Section waste tray and collection system

Microtomes are designed with section waste trays and collection systems, facilitating easy retrieval and organization of tissue sections. This feature enhances workflow efficiency and reduces the risk of section loss or contamination.

 
 

Ergonomic design

 

Microtomes have undergone ergonomic improvements, offering user-friendly interfaces, adjustable handwheels, and comfortable hand rests. These design enhancements prioritize user comfort, reducing fatigue during extended sectioning sessions.

 

 

Semi-automatic Microtome

Type of Microtome

 

 

Sliding microtomes

The advantage is that it guarantees a stable cut, with a thickness of 1 to 60 μm.

Rotation microtomes

Offers a uniform cut that allows to prepare samples between 1 and 60 μm.

Freezing microtomes

They are a subgroup of the rotation microtomes, but instead test is found in a freezer container increasing the hardness of the test.

Ultramicrotome

Allows cuts of extremely thin preparations, driven by thermal expansion, allowing a thickness of 10 to 500μm.

Laser microtomes

They allow very fine special cutting without thermal damage to the test, with a thickness of 10 to 100μm.

 

Applications of Microtome
 

Histological analysis
Microtomy is essential for the preparation of thin, uniform sections of tissue specimens for microscopic examination. These sections are then stained and mounted onto slides for histological analysis. Microtomy enables the visualization of cellular and tissue structures, aiding in the diagnosis and characterization of diseases in diagnostic pathology. It also facilitates research by providing crucial insights into the morphological features of tissues and cells.

 

Immunohistochemistry (ihc)
Microtomy is often employed in immunohistochemistry, a technique used to detect and localize specific proteins or antigens in tissue sections. Thin sections prepared by microtomy allow for optimal antibody penetration, maximizing the sensitivity and accuracy of ihc analysis. By facilitating the visualization of protein expression patterns, microtomy helps researchers and pathologists identify disease markers, assess treatment response, and study various biological processes.

 

Molecular pathology
Microtomy also plays a role in molecular pathology, where it is used for the preparation of tissue sections for molecular analyses, including DNA or rna extraction, in situ hybridization, and fluorescence in situ hybridization. By obtaining well-preserved and properly sectioned tissue samples, microtomy ensures the accuracy and reliability of molecular studies, enabling genetic and genomic analysis, studying mutational profiles, and guiding personalized therapies.

 

Tissue banking and research repositories
Microtomy is instrumental in the creation of tissue banks and research repositories. By cutting and mounting thin sections of tissue samples, microtomy facilitates their preservation and long-term storage. These preserved tissue sections can be utilized for future research studies, retrospective analysis, and validation of findings. The availability of well-preserved sectioned tissues enhances collaborative research and enables the sharing of valuable resources among pathologists and researchers.

 

Slicer Specifications

 

Section thickness

0 to 600µm
0 to 2µm, 0.5µm increments
2 to 10µm, 1µm increment
10 to 20µm, 2µm increments
20 to 100µm, 5µm increments
100 to 600µm, 50µm increments

Trimming thickness

0 to 600µm
0 to 2µm, 0.5µm increments
2 to 10µm, 1µm increment
10 to 20µm, 2µm increments
20 to 100µm, 5µm increments
100 to 600µm, 50µm increments

Retraction thickness

20µm

Specimen horizontal feed

28mm

Specimen vertical feed

70mm

Maximum specimen

40x50x30mm, or standard cassette

Specimen holder adjusted system

Horizontal orientation

±8°

Vertical orientation

±8°

Repositioning of knife holder base(left-right)

50mm

Electric Coarse Feed Speed

750µm/s

Dimension

Length

575mm

Width

405mm (without handwheel, 310mm)

Height

325mm

Weight

About 34kgs

Power supply

100-240 V AC±10 %

Frequency

50/60 Hz

Power

<60 VA

Fuse

2A

 

Certificate

 

 

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FAQ

 

Q: How does a microtome work?

A: It works by freezing the tissue sample and then slicing it into thin sections using a microtome blade within a refrigerated chamber.

Q: What are the main applications of a microtome?

A: Microtomes are mainly used in pathology for rapid diagnosis, in research for studying tissue morphology, and for preparing samples for pathology,histology,research laboratories.

Q: What temperature is typically maintained in a microtome?

A: The chamber is usually maintained at a temperature between -20°c to -30°c.

Q: What are the benefits of using a microtome over a traditional microtome?

A: Microtomes allow for the preservation of tissue morphology and enzyme activity by freezing, enabling faster sectioning and immediate examination of fresh tissue.

Q: Can microtomes be used for all types of tissues?

A: While microtomes are versatile, some tissues with high water content or very fatty tissues May require special preparation to achieve optimal sectioning.

Q: What safety precautions should be taken when using a microtome?

A: Users should wear protective gloves and goggles, handle blades with care, and ensure proper ventilation to avoid exposure to potentially infectious materials.

Q: How thin can sections be cut using a microtome?

A: Microtomes can cut sections as thin as 1-10 micrometers, depending on the sample and the specific microtome model.

Xiaogan Kuohai Medical Technology Co., Ltd. is one of the leading microtome manufacturers and suppliers in China. We warmly welcome you to buy cost-efficient microtome for sale here from our factory. All customized products are with high quality and competitive price. Contact us for OEM service.

Manual Microtome, Tissue Microtome, Automatic Microtome

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