Cryostat

Your Professional Cryostat Supplier

We are your professional Cryostat manufacturer, in 2015, Kuohai was recognized as a "national high-tech enterprise". "Kuohai Medical Technology" has five subsidiaries, including Hubei Xiaogan Kuohai Medical Technology Co., Ltd., Xiaogan Kuohai Medical Technology Co., Ltd., Hubei Haishi Industrial Co., Ltd., Xiaogan Ruifeng Electronic Technology Co., Ltd., Xiaogan Dinghang Decoration Engineering Co., Ltd., and its product range covers medical equipment, biotechnology, electronic technology, high-end building materials, decoration engineering and other industries.

Why Choose Us

Our company
Xiaogan Kuohai Medical Technology Co.,Ltd. is a rare domestic pathology instrument manufacturing company with a widespread user base throughout China. It is also one of the few companies in the domestic and international industry capable of researching, developing, and producing a complete set of pathology instruments and consumables. In 2014, the company established a modern production and processing base.

Our services
All our equipment will be equipped with very detailed instructions, so that your operation is simple and straightforward, and no questions arise. At kuohai medical technology, we guarantee the quality and durability of our products.

Our products
The product range involves medical equipment, biotechnology, electronic technology, high-end building materials, decoration engineering and other industries.

Advantages of Cryostat

Cryostat temperature control

Maintaining consistent low temperatures is essential to preserve tissue integrity during the sectioning process. Most cryostats feature adjustable chamber and cryoplate temperature controls to precisely manage low temperatures. Dual compressor models can independently control the cryoplate and chamber, giving users the flexibility to optimize settings for different tissue types.

Cutting accuracy

The cryostat is designed to produce extremely thin tissue sections, with cutting accuracy adjustable to the micron. This fine control ensures accurate cutting of tissue samples for microscopic analysis. Advanced models May include features such as a vibrating microtome, which uses a vibrating blade to further improve cutting accuracy.

Blade options

Depending on the needs of the laboratory, the cryostat can be equipped with either disposable blades or reusable steel blades. Disposable blades are convenient and do not require sharpening, while reusable blades made from high-quality steel require regular maintenance but can be used over a long period of time. The blade holder is designed to ensure even pressure and stable positioning, which is essential for consistent sectioning quality.

Anti-roll rails

Anti-roll rails prevent tissue sections from curling during the cutting process, ensuring that sections remain flat for easy handling and mounting onto slides. These guides are essential for laboratories requiring high-throughput tissue processing as they minimize waste and ensure consistent section quality.

Applications of Cryostat

Histopathology

This is the study of diseases in tissues. Cryostats can examine sections of tissue or cells.
Molecular biology

Researchers can gain a deeper understanding of biochemical structures and processes by examining sections of tissue.
Immunohistochemistry

Immunohistochemistry is the process of identifying antigens in cells and tissues. This technique helps pathologists diagnose cancer.
Semiconductor manufacturing

Semiconductors are an important component of electronic devices. Advances in electronic components and devices rely on innovative technologies. One way scientists are exploring quantum technology and computing is by testing components and processes in the low-temperature environment provided by cryostats.

Components of a Cryostat

Freezing chamber and cryogenic gas
The freezing chamber and cryogenic gas or fluids allow the cryostat to maintain constantly low temperatures. Researchers May use liquid helium and liquid nitrogen for cooling applications. The freezing chamber is what contains the microtome and cools it while it is sectioning.

Specimen check
Specimen checks mount the samples on the microtome for sectioning.

Microtome
A microtome is a cutting instrument mounted with a sharp, fixed blade. Its mechanism moves the samples toward the blade.

Blade holder

The blade holder clamps either disposable or reusable blades into position.

Anti-roll plates

Anti-roll plates prevent the sections from curling after they have been cut.

Peltier stage

This device removes heat from the cryostat chamber.

Control panel

The control panel makes it possible to operate the instrument. It includes on/off switches, a timer, temperature control and other features.

Specification of Cryostat

Freeze chamber minimum temperature	-35℃±2℃
Freeze shelf minimum temperature	-45℃±5℃
Lowest temperature of Peltier unit on freeze shelf	-55℃±5℃
Lowest temperature of Peltier unit on Specimen Clamp	-50℃±5℃(working time of Peltier is 15 minutes.)
Maximum specimen size	35×35mm
Specimen vertical stroke	48±1mm
Specimen horizontal stroke	15±0.2mm
Coarse feeding speed	300μm/s (slow) or 900μm/s(rapid)
Section thickness range	0μm～100μm adjustable; 0μm～3μm, in 0.5μm increments; 3μm～10μm, in 1μm increments; 10μm～20μm, in 2μm increments; 20μm～100μm, in 5μm increments;
Trimming thickness range	10μm～600μm adjustable; 10μm～50μm, in 5μm increments; 50μm～100μm, in 10μm increments; 100μm～600μm, in 50μm increments;
Retraction range	0~80μm adjustable, in 5μm increments
Voltage and frequency	220 V ± 10%, 50 HZ / 110 V ± 10%, 60 HZ
Nominal Power	1000 W
Weight	About 130 KG
Dimensions(W×D×H)	805×715×1195mm

Certificate

FAQ

Q: What is the purpose of a cryostat?

A: Cryostat: A cryostat is a device that operates at cryogenic temperatures, designed to freeze biological tissues and preserve their integrity during sectioning.

Q: What is the function of the cryostat?

A: A cryostat is a machine used in neuroscience to cut frozen tissue sections for microscopic analysis. It allows tissue to be frozen quickly and then sliced into thin sections that can be mounted on microscope slides for further examination.

Q: What is the use of cryostat in a laboratory?

A: What is a Cryostat? Similar to a standard microtome, a cryostat functions to obtain thin (1-10 mm in thickness) sections from a piece of tissue, but while a standard microtome carries the operation at room temperature, the cryostat enables the operator to section the tissue at low temperature (–20 to –30 C).

Q: What is the difference between cryostat and frozen section?

A: The frozen section is the rapid tissue section by cooling the tissue with the help of cryostat to provide immediate report of the tissue sample. The cryostat is the instrument to freeze the tissue and also to cut the frozen tissue for microscopic section.

Q: What is the advantage of frozen section?

A: Frozen section helps in rapid intra-operative diagnosis. It is commonly used during surgical procedures to detect malignancy so that modifications of surgery can be decided at the time of surgery on the table. Frozen section is also performed for evaluation of surgical margins and detection of lymph node metastasis.

Q: What is the difference between a cryostat and a dewar?

A: A cryostat is a vessel used to maintain cryogenic temperatures and is categorized as a liquid cryostat (referred to as a dewar) or a conduction-cooled (cryogen-free) cryostat. These vessels are vacuum insulated and are constructed of non-magnetic materials with copper or aluminum thermal shields.

As one of the leading cryostat manufacturers and suppliers in China, we warmly welcome you to buy cost-efficient cryostat for sale here from our factory. All customized products are with high quality and competitive price. Contact us for OEM service.

Cryostat, Cryotome, Cryostat Microtome